She starred as Sara Crewe in A Little Princess, a 1995 film adaptation of the Frances Hodgson Burnett classic, and as Alice Marshall in Air Force One.

Her uncle, Jay Pritzker, is the founder of the Hyatt Hotel chain, and owned Braniff Airlines from 1983 to 1988.

[8] Pritzker made her professional stage debut as Scout in a production of To Kill A Mockingbird in Chicago.

She starred in two major films, Alfonso Cuaron's A Little Princess and Wolfgang Petersen's 1997 action thriller Air Force One.

[9] In 2002, Pritzker played the character Jenn in Neil LaBute's play The Distance from Here at the Almeida Theatre at King's Cross in London, England with Enrico Colantoni, Ana Reeder, Amy Ryan, Jason Ritter, and Mark Webber in the cast.

In early 2005, the parties settled the lawsuit, which followed another suit that had begun the process of splitting the family fortune eleven ways.