He is best known for his portrayal of Calogero in Robert De Niro's 1993 directorial debut, A Bronx Tale.

[2] Adopted when he was four months old, he was raised by Italian-American parents, Lillo Brancato Sr., a construction worker, and Domenica, an electrolysist,[3] in Yonkers, New York.

In A Bronx Tale (1993), he played the main character named Calogero, a teenager torn between his father and a mob boss who befriended him as a child (according to New York Magazine, Brancato earned $25,000 ($52,700 today) for the role).

[4] He further appeared in Renaissance Man (1994), followed by a minor but climactic role as a radio operator in Crimson Tide (1995).

Brancato can be heard narrating the music video for the Chris Brown and Young Thug song "City Girls", released on December 4, 2020.

Officers originally pulled Brancato over for having a rear brake light out and found he had an expired registration and no other papers for the vehicle.

He was charged with a Class A misdemeanor for criminal possession of a controlled substance in the seventh degree.

[12] Enchautegui confronted Brancato (then 29) and his accomplice, Steven Armento (48), outside a vacant house located at 3119 Arnow Place, next to his own, after hearing glass break.

[12] Armento (who was the father of Brancato's girlfriend Stefanie) was found to have fired the fatal shot that killed Enchautegui and subsequently convicted of first-degree murder on October 30, 2008, receiving a sentence of life in prison without parole (Armento died on January 2, 2024, at the Mohawk Correctional Facility in upstate New York).