It was converted for home computers and published by U.S. Gold in 1990, and then released for the Master System in 1991; however, the style of the latter was changed to that of an overhead run and gun video game.

The game sees the player placed as a member of a two-man commando team who have been charged with going behind enemy lines to bring down a terrorist organisation which has access to a large arsenal of weaponry.

However, the player is faced with many enemy troops and military vehicles which need to be destroyed in order for the commando squad to escape in the jeep, and must use the "special weapon" against the terrorists.

[10] U.S. Gold acquired the licence to release the game on home computers, and versions were produced for the Amiga, Amstrad CPC, Atari ST, Commodore 64 and ZX Spectrum.

[2] For these versions there is no light gun support: instead the player moves a crosshair using a mouse, joystick or keyboard to target enemies, and pressing a button to fire.

A version developed by Sanritsu for the Master System was published by Sega in 1991, This release is an overhead vertically scrolling shooter, although the storyline and locations are mostly unchanged.

[15] In the United Kingdom, it was one of the top four highest-grossing arcade games during early 1990, along with Teenage Mutant Ninja Turtles, Tecmo World Cup '90 and Super Masters.

Line of Fire received a positive review from S: The Sega Magazine, calling it an "Utterly fab" game with "Amazing 3D graphics" and "heart-stopping action throughout.

"[19] Sean Kelly of Zero magazine called it "the best game" at London's 1990 Amusement Trades Exhibition International (ATEI) and stated that, despite being "an Operation Thunderbolt derivative" it "goes about ten steps better."

[20] CU Amiga gave it an average review with a 66% score, calling it a poor clone of Operation Wolf, with graphics that "aren't as sharp" and lacking dramatic sound.

There was praise for the sit-down cabinet, but the reviewer said this was the only lasting appeal, although they found it a nice touch that defeated enemies stay on the screen rather than disappearing after a few moments, allowing the player to survey the scene they have just created.

[11] Retrospectivaly, Hardcore Gaming 101 praised the graphics, comparing its sprite manipulation to later first-person shooters and textured-mapped 3D polygons, but said the gameplay is "nothing spectacular".