Over time, the buildup of fats may cause permanent cellular and tissue damage, particularly in the brain, peripheral nervous system, liver, spleen, and bone marrow.

Inside cells under normal conditions, lysosomes convert, or metabolize, lipids and proteins into smaller components to provide energy for the body.

[citation needed] Many lipid storage disorders can be classified into the subgroup of sphingolipidoses, as they relate to sphingolipid metabolism.

[citation needed] X-linked recessive (or sex linked) inheritance occurs when the mother carries the affected gene on the X chromosome that has determined the child's gender and passes it to her son.

There are other treatments such as the prescription of certain drugs such as phenytoin and carbamazepine to treat pain for patients with Fabry disease.

Furthermore, gene therapies and bone marrow transplantation may prove to be effective for certain lipid storage disorders.