Darr's previous television appearances include the 1991 short-lived sitcom Flesh 'n' Blood as Rachel Brennan, The WB's teenage drama Popular as Jane McPherson, as well as the short-lived but critically acclaimed 1996 Fox series Profit as Gail Koner.
In the fifth season of the sitcom Ellen, she played Laurie Manning, the girlfriend of the title character Ellen Morgan; In "Four for the Seasaw", an episode of Frasier, she and Megan Mullally played love interests for the Crane brothers.
Darr also made an appearance on the Fox drama House in 2006, playing a victim's mother in the episode "Distractions".
Darr appeared in the fourth season of Weeds (on Showtime) as Ann Carilli.
[2] Her film work includes the Oscar-award-winning Gods and Monsters (1998), in which she appeared as Dana Boone (the wife of Brendan Fraser's character), Pomegranate (2005), as Julia (the mother of Leah Pipes's character) in the soccer film Her Best Move (2006), National Lampoon's Bag Boy (2007), and This Is 40 (2012).