Lisa Adrienne Gladden (born October 6, 1964) is an American politician from Maryland and a member of the Democratic Party.

She resigned as Senator due Multiple Sclerosis on January 10, 2017[1] Born in Baltimore, Maryland, Gladden attended Duke University and the University of Maryland School of Law before entering practice as an attorney in the Office of the Public Defender.

She was active with the American Bar Association, the Alliance of Black Women Attorneys, and with the Democratic Party.

She had been heavily mentored and rose quickly through the ranks, achieving the position of Majority Whip.

Along with Maryland Delegate Curt Anderson, Gladden served as co-chair of the Baltimore for Obama campaign in both the 2008 primary and general elections.