Their long-running collaboration began with an adaptation of the theatrical short Play as part of the Samuel Beckett season for Channel 4, on which she served as editor.
After working on some musical sequences in The Talented Mr. Ripley, her first feature as editor was Minghella's Breaking and Entering in 2006, followed by his pilot for the TV series The No.1 Ladies Detective Agency.
She went on to work as an editor with John Madden on crime thriller Killshot, Salmon Fishing in the Yemen for Lasse Hallström and Seven Psychopaths for Martin McDonagh.
[4] In 2013, she wrote, directed and edited a thirty minute film for the band based on five stories from their album Tales of Us.
In 2021 Gunning directed three episodes of The Power for Amazon Prime Video, based on Naomi Alderman's book of the same name.