[3] She suggested the idea that her husband do his own show based on "practicing preventive medicine on a grand scale".

[11] Oz takes part in speaking engagements across the United States and the world on the subject of well-being and relationships.

[citation needed] In 2011–2012, she collaborated with former Natural Law Party candidate Jeffrey M. Smith in narrating the documentary film Genetic Roulette—The Gamble of Our Lives asserting health risks from GMO foods used in support of a California ballot initiative in favor of GMO labeling.

[14] According to the New York Times, Lisa Oz's mother "believed fervently in New Age approaches like homeopathic remedies and meditation" and also introduced her husband to "alternative medicine and Eastern mysticism" which he now integrates into his advice programs.

[15] They have four children: daughters Daphne Oz, aspiring filmmaker Arabella, and Zoe; and son Oliver.