Born in Rouyn, Quebec, Bissonnette studied education science at the Université de Montréal from 1965 to 1970.
She later pursued doctoral studies at the University of Strasbourg and the École pratique des hautes études in Paris.
She became the parliamentary correspondent in Quebec City, then in Ottawa, before taking on the position of editorialist and, finally, that of writer-in-chief in 1982.
Bissonnette appears regularly as an analyst on both French and English news programs on public and private radio and television networks.
She has also published two novels, Marie suivait l'été (1992) and Affaires d'art (1996), and a short story collection, Quittes et doubles (1997).