List of Pittsburgh Pirates Opening Day starting pitchers

[2] The Pirates have used 71 Opening Day starting pitchers since they began to play as a Major League team in 1882.

Babe Adams and Frank Killen each made five Opening Day starts for the Pirates, and Deacon Phillippe, Howie Camnitz, Cy Blanton and Bob Veale each made four Opening Day starts.

Ed Morris, Pud Galvin, Wilbur Cooper, Ray Kremer, Rip Sewell, Steve Blass, Dock Ellis, Rick Rhoden, Doug Drabek and Francisco Liriano all made three Opening Day starts for the Pirates.

[3] Several Pittsburgh Pirates Opening Day starting pitchers have been elected to the Baseball Hall of Fame, including Galvin, Burleigh Grimes, Waite Hoyt, Jim Bunning, and Bert Blyleven.

[6] Bunning was elected as both a United States congressman and senator from Kentucky after retiring from baseball.

U.S. Senator Jim Bunning was the Pirates' Opening Day starting pitcher in 1968.
Hall of Famer Pud Galvin made three Opening Day starts for the Pirates.
Ed Morris made three Opening Day starts for the Pirates.
Howie Camnitz made four Opening Day starts for the Pirates.