This is the list of notable footballers who have played for Real Betis Balompié.
Generally, this means players that have played 100 or more first division matches for the club.
However, some players who have played fewer matches are also included; this includes the club's founder members, first nationals at the club, and some players who fell short of the 100 total but made significant contributions to the club's history e.g. players who have set a club record such as the youngest player to score, top goalscorer in a season, first La Liga goal ever, etcetera.
[1] Players are listed by nationality and then by beginning of career.
The following players have been selected by their country for the FIFA World Cup finals, while playing for Real Betis.