David Hyde Pierce received numerous awards and nominations for his performance as the titular character's brother, Niles Crane.

The series revolves around the titular character Frasier Crane, a psychiatrist who returns to his hometown to start a new life for himself.

The series stars Kelsey Grammer in role of the main character, as well as Jane Leeves, David Hyde Pierce, Peri Gilpin and John Mahoney.

Several other actors and crew members in the series received many awards and nominations, including Leeves, Mahoney, and the creators of the show.

Frasier received eleven consecutive nominations for Best Casting for TV, Comedy Episodic, one for every season the series was on television, winning five times.

Frasier received nine nominations for the award for Outstanding Directorial Achievement in Comedy Series, three out of nine for work by Pamela Fryman and two of them by David Lee.

Dana Mark McClure, Thomas J. Huth and Robert Douglass won two awards for Outstanding Multi-Camera Sound Mixing for a Series or a Special.

Frasier received 24 Golden Globe Award nominations during its tenure, with two wins for Best Actor – Television Series Musical or Comedy for Kelsey Grammer.

[135] Awarded since 1974, the Humanitas Prize is an annual accolade that recognizes outstanding achievement of writers in film and television whose work promotes human dignity, meaning and freedom.