This article lists the heads of state of Panama since the short-lived first independence from the Republic of New Granada in 1840 and the final separation from Colombia in 1903.

Since 1904 the head of state of Panama has been the President of Panama.

Symbols † Died in office From 1968 to 1989 a military junta exerted a dictatorship over the country and nominated the president, who himself held little power.

The following individuals were leaders of the junta.