Four singles were released from it: "Chandelier", "Big Girls Cry", Sia's solo version of "Elastic Heart", and "Fire Meet Gasoline".

It generated the singles "Alive", her first Billboard Hot 100-topping hit "Cheap Thrills" (solo or featuring Sean Paul), "The Greatest", "Move Your Body", "Reaper" (in Australia), and "Unstoppable" (in 2022).

In 2018, she formed LSD, a supergroup with Labrinth and Diplo; their debut album was released in April 2019 and included the singles "Genius", "Audio", "Thunderclouds", "Mountains" and "No New Friends".

Sia's ninth studio album Music – Songs from and Inspired by the Motion Picture was released on 12 February 2021.

Throughout her career, Sia has recorded and released collaborations with many artists, including Eminem, Wiz Khalifa, Leslie Odom Jr., Angel Haze, Beck, Lior, Giorgio Moroder, Ozuna, Zayn Malik, Doja Cat, BTS, Barney McAll, Gims, Brooke Candy, Miley Cyrus, Diljit Dosanjh, Kylie Minogue, and Kanye West.