The spouse of the prime minister of Belize is not officially defined in the constitution, but the role generally involves a combination of public duties, charity work, and social responsibilities.

The incumbent is Her Excellency Rossana Briceño, who assumed the role on November 12, 2020, upon her husband, Hon.

Rossana Briceño holds a master's degree in Educational Leadership from the University of North Florida and a bachelor's degree in Special Education from Northeastern Illinois University (NEIU).

On January 22, 2021, Rossana Briceño was appointed as the Special Envoy for the Development of Families and Children.

In this capacity, she advocates for the rights and welfare of Belizean families and children, focusing on inclusive education and support for those with special needs.