To date, forty-seven women and three men have been married to a British prime minister in office.

There have also been four bachelor and nine widower prime ministers; the last bachelor was Edward Heath (1970–1974) and the last widower was Ramsay MacDonald (1924, 1929–1935).

The Duke of Grafton (1768–1770) and Boris Johnson (2019–2022) are the only prime ministers to have divorced and remarried while in office.

Over time the position has evolved, and spouses such as Cherie Blair have gained public attention through their own independent careers and achievements, as well as attending engagements such as the African First Ladies Summit.

[1] Cherie Blair, with Cate Haste, wrote a book about recent prime ministerial spouses, The Goldfish Bowl: Married to the Prime Minister, 1955–1997, in 2005.