He was a member of the Backscratchers and over his career was associated with Earl Hooker, Twist Turner, Illinois Slim and Rick Kreher.
[4] In 1950, aged 16, he moved to Chicago, Illinois, and became acquainted with Little Walter, who helped him to learn the rudiments of harmonica playing, and Jimmy Reed.
[2][4] Billed and henceforth commonly known as Little Arthur Duncan, he played primarily in and around Chicago and built up a local reputation over the years.
[2][4] He later appeared on a compilation album, Blues Across America: The Chicago Scene, with Emery Williams Jr. and Robert Plunkett.
One music journalist noted that "spirited, gritty performances of Reed's "Pretty Thing," Wolf's "No Place to Go," and two Dixon favorites ("Young Fashioned Ways" and "Little Red Rooster") leave no doubt that Duncan lives and breathes electric Chicago blues.