According to the 2021 census gazetteer files, Northlake has a total area of 3.18 square miles (8.24 km2), all land.

24.12% of all households were made up of individuals, and 10.91% had someone living alone who was 65 years of age or older.

A Dominick's distribution center was located in Northlake until the supermarket chain's closure in December 2013.

Located in the heart of Northlake, Centerpoint Preserve has become the center of activity for the city.

The park is monitored by several cameras, and the Northlake police department surveys the area often, making it a safe place to work out at night.

[citation needed] Pace provides bus service on routes 309, 318, 319 and 330 connecting Northlake to destinations across the region.