His classmates recall Liu Huan sitting on the stairs of his dorm, playing his guitar and singing songs until midnight.

His song, Asking Myself a Thousand Times (千萬次的問) remained in the top position for ten weeks on Chinese radio stations.

On 19 March 2004, Liu held the first concert in his 19-year career at the Capital Indoor Stadium, Beijing, called "Huange 2004" (欢歌2004).

Other singers included Na Ying, Sun Nan, Sha Baoliang and Warren Mok.

In 2006, Liu held his second concert in the Shanghai Indoor Stadium, with fellow singers Na Ying, Sun Nan, Warren Mok and Song Zuying present as guests.

On 3 July 2007, Liu, Liao Changyong and Warren Mok held a "Zhenhan" music concert in the Great Hall of the People, Beijing.

On 8 August 2008, Liu appeared in front the international audience when he performed the official theme song You and Me with British singer Sarah Brightman at the 2008 Summer Olympics Opening Ceremony in Beijing.

In 2012, Liu was asked to act as one of the four judges on The Voice of China, a singing talent show broadcast on Zhejiang TV.

[6] It was revealed on the final that the song he chose for the final round, which is a three-song medley themed for Empress Xiaoshengxian, was made in tribute to Yao Beina, one of the contestants from the second season of The Voice of China, who died on 16 January 2015, which received a standing ovation from the panel of 500-member judges, and won the season with 62.22% of the votes cast, the highest score attained so far in the history of I Am a Singer.

[11][12] On April 3, 2020, Liu was confirmed to have been diagnosed with Avascular Necrosis, also called osteonecrosis or bone infarction.

[13] During Liu Huan's lectures, he introduces some foreign words when naming people, schools, and locations.

With German and Italian, I only know some terms in these languages, but it doesn’t mean I can speak them.”[9] Singers participated in groups are listed in parentheses.