[6] In 2018, Wheeler was profiled by Politico magazine as a "titan" of conservative media alongside Ben Shapiro, Sean Hannity, Laura Ingraham, Mark Levin, Tucker Carlson, Dana Loesch, and others.

"[10] In a May 2020 segment on OANN, Wheeler claimed without evidence that "mainstream media pretended there was a deadly surge in COVID cases" after the 2020 Wisconsin Spring election.

[14] In an episode posted on June 30, 2021, Wheeler falsely claimed that a "peer reviewed, scientific study showed that the COVID-19 vaccine causes two deaths for every three lives it saves."

The video was flagged by Facebook as part of its efforts to combat misinformation, and PolitiFact found that the MDPI Vaccines journal, which had published the study, had posted a notice raising serious questions about it two days prior to the episode being uploaded.

The notice called the study's conclusions a "misrepresentation of the data" and stated that the authors' assertion that the deaths were caused by vaccination efforts was "incorrect and distorted".

[18] In January 2023, following football player Damar Hamlin's in-game collapse, Wheeler promoted a conspiracy theory that the COVID-19 vaccine was responsible for a "surge" in athlete deaths and injuries.