She has drawn this way for numerous media outlets, including CBS News, The New Yorker, Fusion, NBC and covered live the Oscars, Democratic National Convention, the 2017 Presidential Inauguration, among others.

She writes a regular column for Medium on politics and global women's rights; Donnelly is the author of eighteen books.

[3] Online publications that have published Donnelly's work include Medium, Politico, The Daily Beast,[4] Open Salon,[5] The New Yorker,[6] CNN,[7] Forbes,[8] The Huffington Post,[9] and Women's eNews.

Donnelly's book Cartoon Marriage, written with her husband, was optioned by Jennifer Garner's production company, Vandalia Films.

In October, 2016, Liza was hired by CBSNews to be their "resident cartoonist," drawing and appearing on CBS This Morning and special events.

[24] In May, 2014 received an honorary doctorate from The University of Connecticut, where she also delivered the commencement address to the UCONN Graduate School.