Lizzano (Salentino: Lizzanu; Latin: Licyanum) is a comune of 10,175 inhabitants (2013) in the province of Taranto in the Apulia region of southeast Italy.

The area around Lizzano produces red, white, rose and sparkling Italian DOC wines.

Grapes destined for reds and roses are limited to a harvest yield of 14 tonnes/ha with the finished wine needing to have a minimum alcohol level of 11.5%.

White wine grapes are limited to a harvest yield of 12 tonnes/ha with minimum alcohol level of 10.5% The reds, roses and frizzante roses are blends composed primarily of Negroamaro (60-80%) with Montepulciano, Sangiovese, Bombino nero and Pinot noir making up the remaining.

[3] Lizzano has a Hot Summer Mediterranean Climate with an annual average temperature of 17.45 C.