The church can trace its origins back to a Religious Society in the 18th century, the existence of which predated the visits of John and Charles Wesley in 1740–1742.

They initially met in members' houses and also made use of barns in what was then a rural village.

After the opening of Llanishen railway station in 1871 the village began to develop and new housing was built, leading Llanishen to begin to transform from a village into a suburb of Cardiff.

In response to the potential increase in congregation numbers, the Roath Road Wesleyan Methodist Circuit planned a new chapel for Llanishen (a new one in Birchgrove would soon follow), with the founding stone being laid in 1900.

[1] The church became a grade II listed building in 1999 as "a complete, compact Edwardian chapel in late Gothic style by the pre-eminent Cardiff architect of the period.