The area has extensive evidence of Neolithic settlement and a Bronze Age burial site was discovered behind the school in the 19th century.

Field enclosures on White Hill (a ridge above the village) provide evidence of Roman occupation probably linked to the nearby fortress town of Cunetio.

The collapse of the nearby settlement of Shaw as a result of the Plague may have triggered growth as Lockeridge was situated at an intersection of a major east–west route (now the A4) and a crossing of the Pewsey Downs.

At the roadside entrance are brick walls of the same period, cast iron gates and piers topped with pineapples;[4] Pevsner noted their large size.

[7] Walks from the village lead through the West Woods onto the Pewsey Downs and the Wansdyke,[8] an early medieval earthwork that ran from near Andover to the Bristol Channel and became the border between the Anglo-Saxon kingdoms of Mercia and Wessex.

The Kennet Valley Church of England Primary School draws children from Lockeridge and nearby villages.

The first building for Overton cum Fyfield National School, designed by C. E. Ponting, opened in 1875[9] and by 1906 was attended by 117 pupils.

Kennet Valley Cricket Club has its ground next to the village hall, drawing members from Lockeridge as well as West Overton, East Kennett and Fyfield.

[12] The Lacket, an 18th-century thatched cottage on the southwest edge of the village,[13][14] was bought in 1908 as a weekend retreat by the politician and writer Hilton Young (later Baron Kennet), and was rented in 1914–15 by the author Lytton Strachey.