"Loco" (English: "Crazy") is the lead single from Jowell & Randy's album El Momento released on February 27, 2010.

A remix features reggaeton duo Wisin & Yandel, was released later on June 15, 2010.

The remix version was performed on the 2010 Premios Juventud on July 15, before that, Wisin & Yandel performed their single "Irresistible", including a choreography by the dancers of Step Up 3D dancing behind them.

[2] A music video for both versions (album version & remix) was filmed since February 23, 2010 in San Juan, Puerto Rico directed by Music video director Ulysses Terrero.

The video for the album version was premiered on March 30, 2010,[3] while the remix version with Wisin & Yandel was premiered on July 8, 2010.