The drinking water is not available for the public and used exclusively by researchers who temporarily reside on the island for short periods of time.

Loggerhead Key is likely the driest place in Florida with the lowest amount of precipitation inches and precipitation days, being far from the Florida mainland where afternoon thunderstorms form with ease over the land.Loggerhead Key is named after the loggerhead sea turtle, an endangered marine reptile and species of sea turtle with a cosmopolitan distribution throughout the world.

[4] The flora of Loggerhead Key includes mangrove, coconut palms, geiger trees, morning glory, sea lavender and cactus.

[8] In August 2016, a National Park marine biologist stated that 113 loggerhead turtle nests existed on the island at that time.

[7] In 1972, hundreds of rhesus macaque monkeys were brought from India to Loggerhead Key by Charles River Laboratories.

[14][15] Due to safety concerns regarding the hurricane season, research only occurred in the late spring and summer months.