A part of it belongs to the Polistovsky Nature Reserve, one of the first wetland preserves in Russia, founded in 1994.

The area was populated since medieval times and was located on the waterways which connected Novgorod and Pskov with Velikiye Luki.

On August 1, 1927, the uyezds were abolished and Loknyansky District was established, with the administrative center in the work settlement of Loknya.

The governorates were abolished as well and the district became a part of Velikiye Luki Okrug of Leningrad Oblast.

On January 29, 1935, the district was transferred to Kalinin Oblast, and on February 5 of the same year, Loknyansky District became a part of Velikiye Luki Okrug of Kalinin Oblast, one of the okrugs abutting the state boundaries of the Soviet Union.

On August 22, 1944, the district was transferred to newly established Velikiye Luki Oblast.

It included parts of former Velikoluksky and Kholmsky Uyezds, and its administrative center was located in the selo of Troitsa-Khlavitsa.

[10] On August 1, 1927 Nasvinsky District was also established, with the administrative center in the settlement of Nasva.

[10] On June 1, 1936, Ashevsky District with the administrative center in the selo of Chikhachyovo was established.

[10] On March 10, 1945, Podberezinsky District with the administrative center in the selo of Podberezye was established.

[12] The railway connecting St. Petersburg and Vitebsk crosses the district from north to south.

Loknya is connected by roads with Bezhanitsy (with access to Porkhov and Novorzhev), with Kholm, and with Velikiye Luki.

[13] The federal monuments are the Trinity Church in the village of Miritinitsy, the Intercession Church in the village of Medvedovo, as well as four archaeological sites and the location where Alexander Matrosov was killed in battle in 1943 when he blocked a German machine gun fire with his body.