Lone Tree Creek, formerly Dry Creek, a stream and tributary to the San Joaquin River, flowing in San Joaquin County and Stanislaus County, central California.

It is named for the settlement of Lone Tree, about 2 1/4 miles northeast of present day Escalon.

Its headwaters, in the Sierra Nevada foothills, are now 3.4 miles northwest of Oakdale, about 550 ft. southwest of the end of Parson Ranch Road, in Stanislaus County.

Originally its source in the foothills was a few miles to the east, but its upper reaches were subsequently diverted for irrigation.

Their confluence forms French Camp Slough, a primary tributary of the San Joaquin River.