Lords of Creation is a science fiction novel by American author Eando Binder (combined pseudonym for American brothers Earl and Otto Binder).

It was first published in book form in 1949 by Prime Press in an edition of 2,112 copies, of which 112 were signed, numbered and slipcased.

The novel was originally serialized in six parts in the magazine Argosy beginning September 23, 1939.

He befriends the people of North America who have been conquered by the Antarkans.

The Lady Ermaine falls in love with him and enables his escape.