He played in orchestras, touring internationally, with conductors including John Axelrod, Andrey Boreyko, Fabio Luisi and Riccardo Muti.

He conducted repeatedly at the Sydney Opera House, Gounod's Faust, Verdi's Aida and Puccini's La Bohème.

[2][3] He conducted Giordano's Fedora at the Oper Frankfurt whe the work was first performed at the house in 2022,[4] directed by Christof Loy, with Nadja Stefanoff and Jonathan Tetelman in the leading roles.

[3][5] Reviewer Jan Brachmann from the FAZ noted that he led the orchestra "bright awake" (hellwach) and with sensitivity, letting the singers dominate even when singing softly.

[5] Another reviewer summarised: "Long forgotten and neglected, Passerini brings this opera to new life in a fresh, sparkling and supremely elegant dramatic conducting" ("Die lang vergessene und vernachlässigte Oper lässt Passerini in einem frischen, spritzigen und überaus elegant dramatischen Dirigat zu neuem Leben erwecken").