Among the qualities frequently noted by the critical press are his virtuosic coloratura technique, sumptuous tone, and vivid stage presence.
Among the conductors he collaborated with are Simon Rattle, Riccardo Muti, Lorin Maazel, Colin Davis, Claudio Abbado, Riccardo Chailly, Daniele Gatti, Nikolaus Harnoncourt, Jesús López-Cobos and Marcello Viotti.
He has made Baroque music recordings and took part in live performances with such specialists of the genre as René Jacobs, Emmanuelle Haïm, Rinaldo Alessandrini, Jean-Christophe Spinosi, Fabio Biondi, Claudio Scimone, and Andrea Marcon.
His operatic début (in Rossini's L'inganno felice) took place in 1994 at the Pesaro Festival.
[2] His discography includes Le Nozze di Figaro (with René Jacobs), which won the Grammy Award in the category of Best Opera Recording; two recitals: Chante Venise and Vivaldi: Arie per Basso (Naïve; with Rinaldo Alessandrini) for both of which Regazzo received the "Orphée d'or" awards.