[2] The Loreto Sisters purchased Mandeville Hall in 1924 having previously established schools in Ballarat and Albert Park with encouragement from St Mary MacKillop.

[4] Loreto Mandeville Hall had a co-educational Early Learning Centre established in 2002 which was in partnership with St. Kevin's College.

The school also has a long association with St Mary's College at the University of Melbourne which was also established by the Loreto Sisters.

[6] Loreto Mandeville Hall offers a range of Victorian Certificate of Education (VCE) subjects, approximately 28.

The school operates an Individual Differences program from Prep to Year 6 to acknowledge in the subjects of English and Mathematics to support high achieving students.

Opportunity is also provided for students to participate in; In 2018 and 2020, Loreto Mandeville Hall was the top ranked Catholic girls school in Victoria.

[7] In 2020, students achieved the following VCE results, with seven students receiving the Premier's VCE Award;[8][9][10] Median ATAR of 90.8 The Positive Education curriculum is based on the PERMA model developed by Professor Martin Seligman with the addition of Positive Health.

Barry (yellow)Mornane (green)Mulhall (red)Ward (blue) The Houses compete in several inter-house events including sport, musical arts and theatre studies.

The program offers more than 20 different sports: tennis, athletics, softball, water polo, basketball, swimming, surf lifesaving, soccer, diving, badminton, rowing, volleyball, golf, netball, cross country, snowsports, hockey, cricket, AFL and gymnastics/aerobics.

[15] The school Rowing Squad comprises over 170 athletes from Years 9-12 who compete in the annual Head of the Schoolgirls’ Regatta.

[18] Loreto Aquatic has a number of squads that range from teams for students, to athletes competing at State and National levels.