[9][5] As a country music singer, George performed widely in the United States and visited Germany and Japan.
He sang "Fear of Being Alone" over the credits of Stuck on You, a comedy feature film about a pair of fictitious conjoined twins.
[10] As conjoined twins, Lori and George appeared in a number of television documentaries and talk shows.
They also acted in an episode of the television series Nip/Tuck in which they played conjoined twins, Rose and Raven Rosenberg.
[11] The Schappell twins lived in a two-bedroom apartment with each maintaining a distinct private space.
[13] Guinness World Records declared Lori and George to be the first set of conjoined twins to have different gender identities.
[15][16] Lori and George Schappell died at University of Pennsylvania Hospital on April 7, 2024, at the age of 62.