[3][4] Keane joined the TV3 news team from her position as manager of AA Roadwatch, where she had worked for the previous seven years, broadcasting live on Radio 1 and 2FM every day.
Since leaving TV3, Keane presented the TV Now Awards, The Ultimate Girls Day Out at the RDS, Dublin from 29–31 August 2009 and became Irish spokesperson for Garnier.
In 2012 Keane embarked on a national theatre tour starring in the Louise Roche production Girls Night The Musical, playing the role of Liza, a middle-aged frustrated housewife.
In 2018 she founded Fashion Relief – a fundraising initiative in association with Oxfam to raise funds for famine in Africa.
These have included introducing Charles, Prince of Wales on his first visit to Dublin and welcoming U.S. President Bill Clinton, during his term in office, at an Irish-American ceremony in New York.
Michael O'Doherty, the owner of the VIP publishing group, has compared Keane to the famous television personality from the United Kingdom, Anthea Turner, who he said "was huge in those days".