In the fictional universe of Breaking Bad, Los Pollos Hermanos is featured as a front organization for Gus Fring's methamphetamine manufacturing and distribution operation, but is also highly regarded by the general public of the Southwest as a regional chain on par with KFC.

Los Pollos Hermanos was founded by Chilean nationals and business partners Gus Fring (played by Giancarlo Esposito) and Max Arciniega (James Martinez) in Mexico.

The company eventually became a subsidiary of a fictional German shipping conglomerate, Madrigal Electromotive GmbH, whose connections Fring used to further increase the outreach of both his legal and illegal operations.

Topanga Productions, a subsidiary of Sony Pictures, the producer of Breaking Bad, began selling merchandise including T-shirts and hats displaying the Los Pollos Hermanos logo.

It was announced to open from April 9–10 in New York City on Pearl Street, although the pop-up only offered curly fries and not chicken at all, possibly to avoid NYC Health violations.

[15] On January 20, 2018, to celebrate the 10th anniversary of the beginning of Breaking Bad, the Twisters location used to film the restaurant on the show was temporarily renovated for a single day to look like Los Pollos Hermanos.

[21][22] In late 2019 the "Breaking Bad Experience" pop-up restaurant operated on 7100 Santa Monica Boulevard in West Hollywood, California, and included items reminiscent of Los Pollos Hermanos.