In Long Island, he graduated from Uniondale High School where he attended a two-year trade program in diesel mechanics with the Board of Cooperative Education Services, better known as “B.O.C.E.S.” While B.O.C.E.S.
After retiring from the military, Lou earned an Associate's Degree in Human Behavior from Central Piedmont Community College in Charlotte, NC.
A fabricator at heart, he turned his sights on building muscle cars, starting with transmissions, brackets, roll cages and chassis and performance parts.
3 Lefts Don't Make a Right has featured top-line who’s who in the automotive world, including guests such as 'Richard Rawlings, Wayne Carini, John Schneider, Courtney Hansen, Gene Winfield, Rick Dore, John D’Agostino, Craig Jackson, Stacey David, Linda Vaughn, Joe and Amanda Martin, Ian Roussel, Ralph Gilles, Dennis McCarthy, Faye Hadley, Bogi, Cristy Lee and Bad Chad'.
Using space donated by Strutmasters founder Chip Lofton, Santiago set up a shop at Roxboro, NC, and launched his own channel on YouTube, Garage Insider TV.
With projects ranging from a ground-up restoration of a classic Chevrolet Chevelle to rebuilding an engine on a Chevy Suburban, Santiago uses the program as a "How To" resource for car enthusiasts everywhere.