[1] He was appointed Grand Chamberlain of France in 1644,[2] shortly after the Guises were permitted to return from their exile in Florence.

As Colonel General of the light cavalry, he served as a volunteer at the siege of Gravelines in 1644, and in two other campaigns.

He died in Paris from a wound in his right arm, received on 22 April 1654,[3] while charging the enemy near Arras.

He married on 3 November 1649, in Toulon, Marie Françoise de Valois (d. 1696),[4] daughter of Louis Emmanuel, Duke of Angoulême, who succeeded her father in 1653.

Mentally unstable (imbécile),[4] she was confined, by her mother, to the chateau of Ecouen or at the Hotel d'Angoulême.