The surviving gunners manned heavy artillery pieces in the defenses of Richmond, Virginia, and the battery's remnant surrendered at Appomattox.

During the Seven Days Battles, the regiment fought at Oak Grove on 25 June and Malvern Hill on 1 July, sustaining 214 casualties.

[4] Among Jackson's gunners, only Major L. M. Shumaker's battalion of Brigadier General William E. Starke's division was posted in a good artillery position.

Union Brigadier General Henry Jackson Hunt's 20-pounder Parrott rifles raked the position at long range, causing casualties.

[3] At Fredericksburg, the battery was part of Captain Joseph W. Latimer's artillery battalion in Brigadier General Jubal Early's division, Jackson's Second Corps, Army of Northern Virginia.

[12] At the Battle of Chancellorsville on 1–3 May 1863, Thompson's Louisiana Guard Battery was assigned to Lieutenant Colonel Hilary P. Jones' artillery battalion in Brigadier General Raleigh Colston's division, Jackson's Second Corps.

[15] At the Second Battle of Winchester on 15 June 1863, Ewell's Second Corps trapped a Union division led by Brigadier General Robert H. Milroy and inflicted 4,443 casualties, including 3,358 captured.

On 2–3 July, the battery was temporarily attached to Brigadier General Wade Hampton's cavalry brigade and took losses of 1 killed and 5 wounded.

When Lee found that the Union Army of the Potomac sent two corps to the Western Theater of the American Civil War, he briefly went on the offensive.

However, at 5 pm on 7 November, Brigadier General David Allen Russell's Union division overran the bridgehead and seized the pontoon bridge before the defenders could escape.

Together with a smaller fiasco at Kelly's Ford, the Second Battle of Rappahannock Station cost the Confederates 2,023 casualties, against a Federal loss of 419.