[7] The entire route closely parallels US 71 (largely co-signed with US 167), running on the opposite side of the Union Pacific Railroad tracks through Meeker and Lecompte to Lamourie.

LA 456 served as the original alignment of US 71 and its predecessor, the Jefferson Highway auto trail.

As of 2019, it is under agreement to be removed from the state highway system and transferred to local control.

LA 466 originally consisted of 16 hyphenated routes designated in the 1955 Louisiana Highway renumbering.

Louisiana Highway 469 (LA 469) runs 2.45 miles (3.94 km) in Fort Johnson North.

In Verda, the route turns slightly westward and runs concurrent with LA 122 for about 1 mile (1.6 km).

Before the 1955 renumbering, LA 471 was a small part of State Route 5, which was followed by the original alignment of US 167.

[30] LA 478 heads east from Vowells Mill through the Kisatchie National Forest.

Louisiana Highway 480 (LA 480) runs 24.5 miles (39.4 km) from Coushatta to Clear Lake.

Louisiana Highway 481 (LA 481) runs 10.96 miles (17.64 km) in De Soto Parish.

Louisiana Highway 482 (LA 482) runs 7.47 miles (12.02 km) from the Toledo Bend Reservoir to Zwolle.

[35] The route heads northeast from US 171 in Noble and curves due north at Sardis.

It immediately curves northeast into the small community of Pelican where it intersects LA 513.

Louisiana Highway 486 (LA 486) runs 13.9 miles (22.4 km) from Clarence to Black Lake.

Louisiana Highway 490 (LA 490) runs 14.96 miles (24.08 km) in a general east–west direction from a local road in Janie to the Red River east of Marco, Natchitoches Parish.

[45] LA 490 is an undivided, surfaced two-lane highway that continues the path of a dirt local road northeast through Janie.

In Chopin, the highway passes through a diamond interchange with I-49 (exit 113) and crosses the Union Pacific Railroad line at grade.

It then passes the entrance to the Martco lumber factory and crosses over the Cane River.

At the end of its route, LA 490 provides access to, and makes a loop in front of, the Red River Lock & Dam #3.

[56] Louisiana Highway 497 (LA 497) runs 8.39 miles (13.50 km) from Glenmora to Forest Hill.