Louisiana Highway 1 (LA 1) runs 431.88 miles (695.04 km) in a southeast to northwest direction from a dead end in Grand Isle, Jefferson Parish to the Texas state line northwest of Rodessa, Caddo Parish.
Louisiana Highway 8 (LA 8) runs 156.27 miles (251.49 km) in a southwest to northeast direction from the Texas state line west of Burr Ferry, Vernon Parish to the concurrent US 425/LA 15 in Sicily Island, Catahoula Parish.
Louisiana Highway 19 (LA 19) runs 33.90 miles (54.56 km) in a north–south direction from US 61 in Baton Rouge, East Baton Rouge Parish to the Mississippi state line north of Norwood, East Feliciana Parish.
[22] Louisiana Highway 23 (LA 23) runs 73.64 miles (118.51 km) in a southeast to northwest direction from Jump Basin Road in Venice, Plaquemines Parish to a junction with LA 428 in Gretna, Jefferson Parish.
[25] Louisiana Highway 26 (LA 26) runs 75.91 miles (122.17 km) in a northwest to southeast direction from the concurrent US 171/US 190 southeast of DeRidder, Beauregard Parish to LA 14 in Lake Arthur, Jefferson Davis Parish.
[30] Louisiana Highway 30 (LA 30) runs 27.84 miles (44.80 km) in a northwest to southeast direction from a point near I-10 in Baton Rouge, East Baton Rouge Parish to the junction of US 61 and LA 431 east of Gonzales, Ascension Parish.
[36] Louisiana Highway 37 (LA 37) runs 42.69 miles (68.70 km) in a southwest to northeast direction from the concurrent US 61/US 190 in Baton Rouge, East Baton Rouge Parish to LA 10 in Greensburg, St. Helena Parish.
[38] Louisiana Highway 39 (LA 39) runs 54.33 miles (87.44 km) in a general north–south direction from a local road southeast of Pointe à la Hache, Plaquemines Parish to I-10 in New Orleans, Orleans Parish.
[46] Louisiana Highway 47 (LA 47) runs 16.31 miles (26.25 km) in a general southeast to northwest direction from a local road in Chalmette, St. Bernard Parish to the junction of two local roads in New Orleans, Orleans Parish.
[48] Louisiana Highway 49 (LA 49) runs 3.92 miles (6.31 km) in a general north–south direction from US 61 to the junction of two local roads in Kenner, Jefferson Parish.
[49] Louisiana Highway 50 (LA 50) runs 0.85 miles (1.37 km) in a north–south direction along Almedia Road in St. Rose, St. Charles Parish.
[50] The route heads northward from an intersection with LA 48 (River Road) at the Mississippi River, crossing both the Canadian National Railway (CN) and Kansas City Southern Railway (KCS) tracks at grade, to a point on US 61 (Airline Highway) just east of an interchange with I-310.
[50][51][52] LA 50 was created in the 1955 Louisiana Highway renumbering, and its route has remained the same to the present day.
[54] Louisiana Highway 53 (LA 53) runs 1.63 miles (2.62 km) in a north–south direction along Central Avenue in Reserve, St. John the Baptist Parish.
It proceeds northward along Central Avenue, crossing both the Canadian National Railway (CN) and Kansas City Southern Railway (KCS) tracks at grade, to a junction with US 61 (West Airline Highway).
[55][56][57] LA 53 was created in the 1955 Louisiana Highway renumbering, and its route has remained the same to the present day.
It intersects the southern terminus of LA 57 (Bayou Sale Road) and proceeds north, eventually crossing a swing bridge over a canal connecting with Lake Boudreaux.
Curving to the northwest, LA 56 skirts the Houma city limits and becomes known as East Main Street.
The route proceeds a short distance further to a T-intersection with LA 24 next to the Houma–Terrebonne Airport in an area known as Presque Isle.
LA 58 crosses a vertical lift bridge over each waterway to connect the two highways southeast of Houma.
[66] LA 58 was created in the 1955 Louisiana Highway renumbering, and its route has remained the same to the present day.
After passing Bogalusa High School, LA 60 narrows to two lanes once again and crosses the Bogue Lusa Creek onto Cumberland Street.
Shortly after passing through the town center, LA 63 makes a brief jog west onto US 190 (Florida Boulevard) before continuing its northward trajectory.
[74] Louisiana Highway 66 (LA 66) runs 19.62 miles (31.58 km) in a general northwest to southeast direction from the main entrance of the Louisiana State Penitentiary at Angola to a junction with US 61 north of St. Francisville, West Feliciana Parish.
[75] Louisiana Highway 67 (LA 67) runs 43.60 miles (70.17 km) in a north–south direction from LA 73 in Baton Rouge, East Baton Rouge Parish to the Mississippi state line north of Clinton, East Feliciana Parish.
[76] As of 2018, the section of LA 67 south of US 190 is under agreement to be removed from the state highway system and transferred to local control.
[88] Louisiana Highway 82 (LA 82) runs 143.14 miles (230.36 km) in a general east–west direction from the Texas state line west of Cameron, Cameron Parish to the Vermilion–Lafayette parish line southwest of Youngsville.
[92] Louisiana Highway 87 (LA 87) runs 42.01 miles (67.61 km) in a northwest to southeast direction from LA 86 in New Iberia, Iberia Parish to a local road north of Centerville, St. Mary Parish.
[95] There is one hyphenated route, LA 89-1, which runs 5.053 miles (8.132 km) also in a north–south direction from a roundabout at Iberia Street in Youngsville, to US 90/LA 182 on the Lafayette–Broussard municipal boundary.