María de Lourdes Cuesta Orellana (born 5 October 1976) is an Ecuadorian politician who was a member of the CREO party until she left.

[1] In 2020 she, Amapola Naranjo and Roberto Gómez, challenged the government minister María Paula Romo that she had failed to fulfil her duties during the national strike in October 2019.

[4] On November 24, the National Assembly, with 104 positive votes, approved the motion to censure and dismiss Romo for allowing harsh police intervention against protesters during that strike.

She was also accused of allowing police to use expired tear gas canisters that endangered people's lives during the eleven days of anti-government protests in Quito.

[5] During the COVID-19 pandemic in Ecuador in August 2020, Cuesta was one of the assembly members who demanded work from the Ministry of Public Health to report on the state of citizens with other diseases.