The episode features anthropomorphic dog Brian as he meets a fellow atheist named Carolyn (Kat Foster) at a book store, and the two begin dating.
Carolyn is led to believe that Brian does not want a substantive relationship, so she begins to date Cleveland (Mike Henry).
Feeling bad for his botched advice that cost Brian a relationship with Carolyn, Stewie suggests that he can convince Cleveland's ex-wife, Loretta, to reconcile with him.
Later, Cleveland visits Brian to clear the air with him but reveals that he plans to elope with Carolyn in Hawaii, which makes their friendship tense.
Just as Cleveland leaves, Loretta arrives and apologizes to him for her affair with Quagmire; she begs him to allow her to get their family back together and promises she will never betray him again.
Quagmire meets her at the hotel she is staying in, but this time, Loretta resists his advances and tells him to leave after smashing his face with an iron.
[4] "Love, Blactually", along with the first eight episodes of the seventh season were released on DVD by 20th Century Fox Home Entertainment in the United States and Canada on June 16, 2009, one month after it had completed broadcast on television.
[5] The "Volume 7" DVD release features bonus material including deleted scenes, animatics, and commentaries for every episode.
[2] The episode begins with a costume party, where Brian and Stewie are both dressed as Snoopy from Peanuts, Quagmire dresses up as Napoleon Dynamite, Peter as Laura Bush, Lois as Michael Dutton Douglas, Joe as Mark Spitz (although people believe he is a crippled Thomas Magnum), and Cleveland as Charlie Chaplin.
[8] The popular conversation between Stewie and Brian which draws attention to a hard "h" consonant sound is directly sourced from dialogue within the film Hot Rod.
Ahsan Haque of IGN praised "Love, Blactually", writing that it had "many memorable scenes, quote-worthy dialogue, politically incorrect references, and great storyline".