Stew-Roids

Peter injects the drugs into Stewie, who becomes incredibly buff and develops an aggressive personality, much to the horror of his family.

Stewie jumps out of his bedroom window to avoid Brian's wrath, only to have his loosened skin help him glide to safety.

As a result, Chris's popularity increases at school, which leads to accolades by the jocks, cheerleaders, and other socially powerful students.

They publicly release a video of Chris dancing naked in his room in the style of Buffalo Bill from The Silence of the Lambs.

Connie instantly becomes popular again, while Chris is rendered back to his low social standing and apologizes to Meg for everything, and he tells her what it was like to be a part of the "in-crowd".

[5] In addition to the regular cast, actors Meredith Baxter-Birney, Jeff Bergman, Gary Cole, Chace Crawford, Camille Guaty, Wentworth Miller, Mae Whitman and Lisa Wilhoit guest starred in the episode.

[6][7] The episode featured many of the show's recurring guest voice actors including: Alexandra Breckenridge, Chris Cox, Ralph Garman, and writers Danny Smith, Alec Sulkin, and John Viener also made minor appearances.

[6] Recurring voice actors Jennifer Tilly and Patrick Warburton reprise their roles of Bonnie and Joe Swanson respectively.

After Stewie's steroids injection wears off and he jumps out the bedroom window, the music playing is from the cartoon series The Rocky and Bullwinkle Show.

[14] Ahsan Haque of IGN gave the episode a score of 8.2 out of 10, commending Chris' storyline and praising Stewie's temporary build, but criticizing the staleness of Meg's continued poor treatment.

Club gave a much more critical review giving the episode a grade of a C. Heisler stated that neither of the storylines "held any water", because they were "ridiculously short".

The PTC's review cited the episode's crude jokes, "tiresome pop culture cutaways" and "its conceit that its content is original."

The sets included brief audio commentaries by Seth MacFarlane and various crew and cast members for several episodes, a collection of deleted scenes, a special mini-feature which discussed the process behind animating "Road to the Multiverse", and mini-feature entitled "Family Guy Karaoke".