It has good traffic accessibility and is located in the Sava and Krka Valleys, with hilly areas with vineyards and an abundance of water.

The only nuclear power plant in the country and Čatež spa are located in the region.

The region annually spends EUR 22 million on environmental protection.

The Lower Sava Statistical Region includes 5 cities and towns, the largest of which are Krško and Brežice.

[7] The Lower Sava Statistical Region comprises six municipalities: The population in 2020 was 70,349.