Collected editions were put out by Aeon and Black Eye Books.

The Comics Journal described the book as following the "frustration and cynicism of disenchanted slacker kids finding excitement in their uneventful lives".

Brubaker cited his work here as an influence on later works: I'm exploring the same themes in my Batman comics and my Catwoman comics that I was probably exploring in Lowlife: family relationships, personal relationships, people not being able to escape their past.

[2] The work is semi-autobiographical, based upon the lives of the author and his friends but "with the names changed".

The series has been collected into a number of trade paperbacks: This comics-related article is a stub.