[2][3] Since its foundation, Loyola Agila has been actively participating in local semi-professional club tournaments; the most notable is the Lotto Titans Football Cup.

[11] The Loyola Sparks had a successful campaign in the 2011 UFL Cup, but eventually lost to the Philippine Air Force 2–0 in the finals.

[12] The Sparks started their 2012 United Football League campaign on a high note, topping all clubs at the end of the first round of competition.

[14] In the preliminary round on 18 May 2012, they played Geylang United, where they won 2–1 in added extra time, advancing them to the two-legged quarter-finals.

[15] They faced Burmese club Kanbawza in early July wherein they defeated them 5–3 on aggregate after a 3–1 win and a 2–2 draw in both legs.

[20] They've played with Harimau Muda B in the 2013 Singapore Cup opening match which ended in favor of the club.

[22] On 30 October 2013, Loyola set a record with the most goals scored in the United Football League, they faced Blue Guards at the Emperador Stadium.

[23][24] Because of that Phil Younghusband currently leads the top scorer of the cup at 18 goals and the team advances to the knockout stages of the tournament.

The sparks ended their 2016 season once again as third placers in the 2016 United Football League, finishing 6 points behind eventual champions Global, lost to Ceres in goal difference.

Also with the group were Club De Fútbol Manila, Don Bosco Garelli and UAAP Season 85 champions Far Eastern University.

[40] Loyola ended their three-game winless run after defeating Don Bosco Garelli United 6–1.

Loyola then lost to Kaya-Iloilo 7–0, ending their Copa Paulino Alcantara campaign with one win, one draw, and three losses.

[41] In early December 2023, after a five-season absence, Loyola announced their return to Philippines Football League through social media.

The "Loyola" name was a contraction of the words Lobo y Olla which literally meant "wolf and pot" in Spanish.

Loyola being a national team player-laden club, was known for having a fanbase mainly composed of fangirls who were avid supporters of the Philippine Azkals.

The rivalry began in the 2011 UFL Cup semi-finals clash between the two teams, in which Kaya went up to lead the game by 3–0 only to lose by 4–5 after an enthralling comeback from the Sparks.

Since then, the UFL has had some of its highest attendance numbers whenever there are match-ups between the two teams, making the rivalry the most famous derby in Philippine club football.

However, after the first season of the PFL concluded, Meralco (Loyola) then decided to pull out of the league and Kaya moving to Iloilo City, effectively ending the rivalry between the two clubs.

The rivalry with Philippine Air Force started when Air Force defeated the national team player-laden Loyola 2–0 during the 2011 UFL Cup final, Edmundo Mercado Jr., adjudged the best goalkeeper of the tournament, defiantly and somewhat controversially proclaimed his side as "true Filipinos".

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.