Luca Campogrande grew up in the youth sector of Sam Basket Roma, where he achieved the title of Italian U-19 Elite champion in 2015.
[1] The following year he went to Fortitudo Bologna, for the first time he played in Serie A2 League, where he signed a two-year deal.
[3] On 6 July 2018 Campogrande signed a deal with LBA club Sidigas Avellino.
After that he first joined Reyer Venezia for trainings[8] and soon after, on 18 December, he was signed until the end of the season.
[10] On 25 July 2023, Campogrande signed a one-year contract with Pallacanestro Trieste.