[1][2][3] Supporter of initiatives to tackle climate change,[4][5][6] gender-affirming surgery,[7][8] the recognition of transgender people to identify with their preferred sex,[9] and main protagonist of the fight against homophobia[10] and antisemitism,[11][12] he often rose to prominence for his positions contrasting the lines of his own party, in particular for the ones concerning the welcoming of immigrants[13] and his model of "integrazione diffusa" (a redistributive framework where immigrants' quota are spread across municipalities) of migrants coming to Europe.

After starting with the graduation party organized by him, for twelve years he worked as a PR for various discos in his area such as the "Manhattan" of Godega di Sant'Urbano, the "Diamantik" of Gaiarine, the "Kolossal" of Spresiano or the "Desiree" in Caorle, in addition to various other jobs, including "the waiter, the cleaner, the bricklayer, the private chemistry teacher, the horse riding instructor, the worker in a leather company.

Luca Zaia joined Liga Veneta–Lega Nord in the early 1990s, after having met Gian Paolo Gobbo, and was first elected to public office in 1993, when he became municipal councillor of Godega di Sant'Urbano.

[15][16] In December 2009, The People of Freedom (PdL) determined that the coalition candidate in the 2010 regional election would be a member of Lega Nord.

The demonstration was supported by Zaia, who demanded a "return to legality", even though his predecessor Giancarlo Galan, a member of his coalition, was in favour of GMOs.

After a flood in 2010, Zaia and his coalition changed a regional law to permit the reconstruction of rural ruins up to 800 cubic metres.

In February 2020 Zaia apologized after criticizing China over the COVID-19 pandemic and claiming that Chinese people "eat live mice".