Ludwig Boltzmann Institute for Functional Brain Topography

The institute was composed of several study groups doing research on the following topics:[1] After the movement-related potentials had been investigated by Elektroencephalography (EEG) and by Magnetoencephalography (MEG) (Bereitschaftspotential BP or readiness potential),[2] the visiting scientist Ross Cunnington was improving the temporal resolution of the fMRI (Functional magnetic resonance imaging) to an extent that Bereitschaftspotential characteristics in regional cerebral blood flow (rCBF) could be recorded (Event-related fMRI).

In order to investigate the brain activity of music students while composing, the study group Beisteiner selected two methods: Cortical DC-potentials of the EEG and MEG.

[7] The study group Beisteiner also provided the pre-operative analysis of patients scheduled for surgery (with fMRI, MEG and DC-EEG).

[8][9] With 14 early blind subjects the study group Uhl was able to show that specific changes occurred in occipital and basal temporo-occipital brain areas only, whereby the primary visual cortex plays an important role.

This brain activity is the Readiness Field (RF) or Bereitschaftsfield (BF) and in particular its left-lateralized component BF2 prior to the fluent speech production.

By investigating 30 patients of this chronic neurological condition, it was revealed that not only the localisation of the epileptic dipole in the temporal region, but also its orientation in space is important.

This led to the classification of two subtypes of patients with medial temporal lobe epilepsy, who have different distribution of the seizures (unilateral or bilateral) and also different prognosis.