In 1680 Garzi was appointed Regent of the Congregazione dei Virtuosi al Pantheon, the papal society of painters.
Garzi joined Rome's guild of painters, The Accademia di San Luca, in 1670 and became a director in 1682.
He painted a St Silvestro shows Constantine portraits of Saints Peter and Paul for Santa Croce in Gerusalemme.
In the early 1680s, he contributed to the frescoes on the vault of San Carlo al Corso, where his works included an Allegory of Faith.
He also completed a fresco depicting the Glory of the Eternal Father (1686) for the dome of the Cybo Chapel in the church of Santa Maria del Popolo.